Perform comprehensive gene enrichment analysis including Gene Ontology (GO), KEGG, Reactome, WikiPathways, and MSigDB enrichment using both Over-Representation Analysis (ORA) and Gene Set Enrichment Analysis (GSEA). Integrates local computation via gseapy with ToolUniverse pathway databases for cross-validated, publication-ready results.
IMPORTANT: Always use English terms in tool calls (gene names, pathway names, organism names), even if the user writes in another language. Only try original-language terms as a fallback if English returns no results. Respond in the user's language.
| genelist | Yes | List of gene symbols, Ensembl IDs, or Entrez IDs | ["TP53", "BRCA1", "EGFR"] | | organism | No | Organism (default: human). Supported: human, mouse, rat, fly, worm, yeast, zebrafish | human | | analysistype | No | ORA (default) or GSEA | ORA |