domain-research-health-science

SKILL.md

This skill helps structure clinical and health science research using evidence-based medicine frameworks. It guides you through formulating precise research questions (PICOT), evaluating study quality (hierarchy of evidence, bias assessment, GRADE), prioritizing outcomes (patient-important vs surrogate), and synthesizing evidence for clinical decision-making.

Trigger phrases: "clinical trial design", "systematic review", "PICOT question", "evidence quality", "bias assessment", "GRADE", "outcome measures", "research protocol", "evidence synthesis", "study appraisal"

Domain Research: Health Science applies structured frameworks from evidence-based medicine to ensure clinical research is well-formulated, methodologically sound, and clinically meaningful.

在制定临床研究问题（PICOT框架）、评估健康证据质量（研究设计层次结构、偏倚评估、GRADE）、优先考虑患者重要结果、进行系统评价或荟萃分析、为指南创建证据摘要、评估监管证据或当用户提及临床试验、循证医学、健康研究方法、系统评价、研究方案或研究质量评估时使用。 来源：lyndonkl/claude。

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