domain-research-health-science

SKILL.md

This skill helps structure clinical and health science research using evidence-based medicine frameworks. It guides you through formulating precise research questions (PICOT), evaluating study quality (hierarchy of evidence, bias assessment, GRADE), prioritizing outcomes (patient-important vs surrogate), and synthesizing evidence for clinical decision-making.

Trigger phrases: "clinical trial design", "systematic review", "PICOT question", "evidence quality", "bias assessment", "GRADE", "outcome measures", "research protocol", "evidence synthesis", "study appraisal"

Domain Research: Health Science applies structured frameworks from evidence-based medicine to ensure clinical research is well-formulated, methodologically sound, and clinically meaningful.

Use when formulating clinical research questions (PICOT framework), evaluating health evidence quality (study design hierarchy, bias assessment, GRADE), prioritizing patient-important outcomes, conducting systematic reviews or meta-analyses, creating evidence summaries for guidelines, assessing regulatory evidence, or when user mentions clinical trials, evidence-based medicine, health research methodology, systematic reviews, research protocols, or study quality assessment. Source: lyndonkl/claude.

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