Comprehensive pathway and systems biology analysis integrating multiple curated databases to provide multi-dimensional view of biological systems, pathway enrichment, and protein-pathway relationships.
| Reactome | Human-curated reactions & pathways | Detailed mechanistic pathways with reactions | | KEGG | Reference pathways across organisms | Metabolic maps, disease pathways, drug targets | | WikiPathways | Community-curated pathways | Emerging processes, collaborative updates |
| Pathway Commons | Integrated meta-database | Aggregates multiple sources (Reactome, KEGG, etc.) | | BioModels | Computational SBML models | Mathematical/dynamic systems biology models | | Enrichr | Statistical enrichment | Pathway over-representation analysis |
Comprehensive systems biology and pathway analysis using multiple pathway databases (Reactome, KEGG, WikiPathways, Pathway Commons, BioModels). Performs pathway enrichment, protein-pathway mapping, keyword searches, and systems-level analysis. Use when analyzing gene sets, exploring biological pathways, or investigating systems-level biology. Source: mims-harvard/tooluniverse.