tooluniverse-literature-deep-research

SKILL.md

A systematic approach to comprehensive literature research that starts with target disambiguation to prevent missing details, uses evidence grading to separate signal from noise, and produces a content-focused report with mandatory completeness sections.

| Gene symbol (EGFR, TP53, ATP6V1A) | Biological target | Phase 1 required | | Protein name ("V-ATPase", "kinase") | Biological target | Phase 1 required | | UniProt ID (P00533, Q93050) | Biological target | Phase 1 required | | Disease, pathway, method | General topic | Phase 1 optional | | "Literature on X" | Depends on X | Assess X |

CRITICAL: This phase prevents "missing target details" when literature is sparse or noisy.

Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction. Creates a detailed report with mandatory completeness checklist, biological model synthesis, and testable hypotheses. For biological targets, resolves official IDs (Ensembl/UniProt), synonyms, naming collisions, and gathers expression/pathway context before literature search. Outputs report-only by default; methodology in separate appendix if requested. Use when users need thorough literature reviews, target profiles, or ask "what does the literature say about X?". Source: mims-harvard/tooluniverse.

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