tooluniverse-protein-therapeutic-design
✓Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design, ESMFold/AlphaFold2 for validation. Use when asked to design protein binders, therapeutic proteins, or engineer protein function.
Installation
SKILL.md
AI-guided de novo protein design using RFdiffusion backbone generation, ProteinMPNN sequence optimization, and structure validation for therapeutic protein development.
| NvidiaNIMrfdiffusion | Backbone generation | Yes | | NvidiaNIMproteinmpnn | Sequence design | Yes | | NvidiaNIMesmfold | Fast structure validation | Yes | | NvidiaNIMalphafold2 | High-accuracy validation | Yes | | NvidiaNIMesm2650m | Sequence embeddings | Yes |
| NvidiaNIMrfdiffusion | numsteps | diffusionsteps | | NvidiaNIMproteinmpnn | pdb | pdbstring | | NvidiaNIMesmfold | seq | sequence |
Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design, ESMFold/AlphaFold2 for validation. Use when asked to design protein binders, therapeutic proteins, or engineer protein function. Source: mims-harvard/tooluniverse.
Facts (cite-ready)
Stable fields and commands for AI/search citations.
- Install command
npx skills add https://github.com/mims-harvard/tooluniverse --skill tooluniverse-protein-therapeutic-design- Category
- </>Dev Tools
- Verified
- ✓
- First Seen
- 2026-02-11
- Updated
- 2026-02-18
Quick answers
What is tooluniverse-protein-therapeutic-design?
Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design, ESMFold/AlphaFold2 for validation. Use when asked to design protein binders, therapeutic proteins, or engineer protein function. Source: mims-harvard/tooluniverse.
How do I install tooluniverse-protein-therapeutic-design?
Open your terminal or command line tool (Terminal, iTerm, Windows Terminal, etc.) Copy and run this command: npx skills add https://github.com/mims-harvard/tooluniverse --skill tooluniverse-protein-therapeutic-design Once installed, the skill will be automatically configured in your AI coding environment and ready to use in Claude Code or Cursor
Where is the source repository?
https://github.com/mims-harvard/tooluniverse
Details
- Category
- </>Dev Tools
- Source
- skills.sh
- First Seen
- 2026-02-11