tooluniverse-drug-target-validation

Validate drug target hypotheses using multi-dimensional computational evidence before committing to wet-lab work. Produces a quantitative Target Validation Score (0-100) with priority tier classification and GO/NO-GO recommendation.

| target | Yes | Gene symbol, protein name, or UniProt ID | EGFR, P00533, Epidermal growth factor receptor | | disease | No | Disease/indication for context | Non-small cell lung cancer, Pancreatic cancer | | modality | No | Preferred therapeutic modality | small molecule, antibody, protein therapeutic, PROTAC |

| 80-100 | Tier 1 | Highly validated - proceed with confidence | | 60-79 | Tier 2 | Good target - needs focused validation | | 40-59 | Tier 3 | Moderate risk - significant validation needed | | 0-39 | Tier 4 | High risk - consider alternatives |